Living with MFM

GENETICS

Myofibrillar Myopathies are most often inherited. Most MFMs are Autosomal Dominant.

Patterns of inheritance

Autosomal Dominant

Each affected person has an affected parent Occurs in every generation

Autosomal Recessive

Both parents of an affected person are carriers Not typically seen in every generation

X-linked Dominant

Females more frequently affected Can have affected males and females in same generation

X-linked Recessive

Males more frequently affected Affected males often present in each generation

Mitochondrial

Can affect both males and females, but only passed on by females Can appear in every generation

Welcome to this website put together by people living with MFM. There are many different forms of myofibrillar myopathy. If you would like talk with others with MFM please join us on our Facebook group.

If you are looking for ways to help check out the Advocate page.

Depending on the type of MFM you may experience trouble walking, climbing stairs, breathing, heart problems, or even gripping objects. Of course we can also have a number of other health issues which can complicate a diagnoses. Look through this entire website for a better understanding of MFM.

To learn more about genetics and how to read your test report please watch the video from Simons Searchlight.

Myofibril Contractions are explained with this video. It shows how the muscle works.

Down load this genetics PDF to see the how MFM is passed down.

Join our Facebook group to talk with others with myofibrillar myopathy.